Showing posts with label Gps Application. Show all posts
Showing posts with label Gps Application. Show all posts

Stem cells use GPS to generate proper nerve cells

An unknown function that regulates how stem cells produce different types of cells in different parts of the nervous system has been discovered by Stefan Thor, professor of Developmental Biology, and graduate students Daniel Karlsson and Magnus Baumgardt, at Linköping University in Sweden. The results improve our understanding of how stem cells work, which is crucial for our ability to use stem cells to treat and repair organs. The findings are publishing next week in the online, open-access journal PLoS Biology.

Stem cells are responsible for the creation of all cells in an organism during development. Previous research has shown that stem cells give rise to different types of cells in different parts of the nervous system. This process is partly regulated by the so-called Hox genes, which are active in various parts of the body and work to give each piece its unique regional identity - a kind of GPS system of the body. But how does a stem cell know that it is in a certain region? How does it read the body's "GPS" signals? And how is this information used to control the creation of specific nerve cells?

In order to address these issues, the LiU researchers studied a specific stem cell in the nervous system of the fruit fly. It is present in all segments of the nervous system, but it is only in the thorax, or chest region, that it produces a certain type of nerve cell. To investigate why this cell type is not created in the stomach or head region they manipulated the Hox genes' activity in the fly embryo.

It turned out that the Hox genes in the stomach region stop stem cells from splitting before the specific cells are produced. In contrast, the specific nerve cells are actually produced in the head region, but the Hox genes turn them into another, unknown, type of cell. Hox genes can thus exert their influence both on the genes that control stem cell division behaviour and on the genes that control the type of nerve cells that are created.
"We constantly find new regulating mechanisms, and it is probably more difficult than previously thought to routinely use stem cells in treating diseases and repairing organs, especially in the nervous system", says Thor.

Funding:This work was supported by the Swedish Research Council, by the Swedish Strategic Research Foundation, by the Knut and Alice Wallenberg foundation, by the Swedish Brain Foundation, by the Swedish Cancer Foundation, and by the Swedish Royal Academy of Sciences to ST. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing interests statement: The authors declare that no competing interests exist.
Citation: Karlsson D, Baumgardt M, Thor S (2010) Segment-Specific Neuronal Subtype Specification by the Integration of Anteroposterior and Temporal Cues. PLoS Biol 8(5): e1000368. doi:10.1371/journal.pbio.1000368

PLEASE ADD THE LINK TO THE PUBLISHED ARTICLE IN ONLINE VERSIONS OF YOUR REPORT: http://biology.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pbio.1000368
PRESS ONLY PREVIEW OF THE ARTICLE: http://www.plos.org/press/plbi-08-05-Thor.pdf
RELATED SYNOPSIS: http://www.plos.org/press/plbi-08-05-ThorSynopsis.pdf

CONTACT
Dr. Stefan Thor
Linkoping University
Dept Clinical Exp Medicine
Linkoping, S-581 85
Sweden
+46-13-22 57 75
stefan.thor@liu.se

Your GPS cellphone makes a Star Trek communicator look like a kid's toy

By Scott Edmonds, THE CANADIAN PRESS


WINNIPEG - So, you've got GPS on your smartphone and can tackle the trip to Uncle Charlie's new house in the suburbs with a fresh sense of confidence.
But are you ready for a trip down the Amazon?
"Interesting, I'd love to do that test," laughs Christ Peralta, head of social location services for Nokia.
"That's a real interesting use case. I wouldn't advise it," says a slightly more definitive Ken Kershner, vice-president of software at Research in Motion's subsidiary Dash.
OK, it was just a thought. And perhaps smartphone GPS isn't ready for the jungles of Brazil, but both men suggest it's perfectly designed for the more urban jungle most cellphone users must deal with every day.
GPS stands for Global Positioning System. It's a worldwide navigation tool, supplied courtesy of the U.S. military, that relies on 24 satellites that transmit their location and the current time.
Signals arrive at GPS receivers at slightly different times based on how far away each satellite is from the receiver. With at least four satellite signals, a receiver can then calculate its position. Hand-held GPS receivers are usually accurate to within 10 to 20 metres.
It's old hat now and in use for commercial navigation, helps hunters find their way in the woods and leads fishermen unerringly back to that hotspot they found last year. It continues to grow in popularity as the cost of receivers comes down.
Cellphones have had GPS locators in them since 2005 because the United States decided it wanted to be able to track cellphone location for emergency purposes after Sept. 11, 2001.
While initially the feature just sat there, cellphone manufacturers were quick to make good use of the application. Besides finding out where you are, or where you're going, you can also keep track of your children, post your location to Facebook or find a lost phone.
Manufacturers are always on the lookout for new ways for customers to use their cellphones and there seem to be few limits on the applications. Smartphones already make the old 'communicator' that once seemed so slick on "Star Trek" look like a kid's toy.
"I think the key is to find out what consumers want," says Peralta. "The second step is to make it easy out of the box."
He says that's what Nokia is trying to do with its latest offering for its smartphones: the preloaded Ovi mapping system that makes them into more effective GPS units.
Onboard maps in a GPS-enabled smartphone mean it can function as an independent GPS unit, without connection to a cellphone network.
That's a key feature for anyone who wants to use their GPS-enabled phone while travelling and doesn't want to incur hefty roaming or long-distance charges.
"It can be a travel companion when you travel abroad . . . or can help you rediscover your city," says Peralta. "There are features that require online connections. . . but the consumer has the choice."
All of the new Ovi-loaded Nokia GPS smartphones can function without connection to a cellular network, he says.
Just how popular is the GPS feature in cellphones? A recent Angus Reid survey for Nokia found that 38 per cent of Canadians use some form of GPS device, but most use a traditional portable unit. So far, only eight per cent use it on their cellphone.
But that's already twice as many as use an installed in-car device. The survey of 1,000 people is considered accurate to within plus or minus 3.1 per cent, 19 times out of 20.
There have been suggestions that cellphone GPS might someday replace stand-alone devices. Kershner says it can replace the stand-alone units, "in some uses."
"It depends how much value you place on GPS." And, he adds, how much you're willing to pay. Cellphones are pretty near the bottom of the price point, considering what else they offer.

But function is also important and all GPS devices have their requirements and capabilities. The most expensive can cost thousands of dollars and are also the most accurate, using other aids to further refine position to within a metre in some cases.
But what if you want to use your GPS-equipped smartphone in your car, for example.
First, there are power requirements that have to be met. Turning on the GPS chip in a phone means it uses power faster. So if it's being used in a car, it needs to be able to connect to the car's power supply.
If it's used in a car it also has to have a large enough screen to be seen easily or have a good text-to-voice feature, so you can hear the instructions to get to your destination (these are what's generally known as a 'turn-by-turn' GPS guidance system). And be sure to check for d
ap-l
BC-20100303-US-FEA-Food-Tiny-Wine-Bottles, Budget
code:8
Budget
Eds:TastingRoom as one word is cct.
See Photos
CP Lifestyle, Beverage, Retail, Food
Vintners hope tiny tasting bottles will pay big dividends in wine marketing
By Michelle Locke

THE ASSOCIATED PRESS
NAPA, Calif. - Thousands of people visit the Domaine Carneros Winery each year, snapping pictures in front of the 18th-century-style chateau and sipping wine on the terrace overlooking a sweep of green vineyards.
Now, the winery hopes to extend the experience with new sample-sized bottle kits that aim to send the tasting room experience home - you read the tasting notes, you sip, you rekindle those sensory memories. All without ponying up for a full bottle of untried wine - or stripping down for an airport security check.
"You can stay in Iowa or New York or Miami, wherever you are, and you can have this experience come to you," says Eileen Crane, CEO and founding winemaker of Domaine Carneros.
The idea seems simple enough. You try sample sizes of drapes, mouthwash and wallpaper. Why not wine?
But test-driving wine isn't as simple as opening a big bottle and pouring it into a bunch of little ones, says Tim Bucher, CEO and founder of TastingRoom Inc., which launched last year and is making the 50-millilitre samples for Domaine Carneros.
For one thing, wine is sensitive to oxygen. So if a little bit is exposed to a lot of oxygen, which is what would happen if you merely poured wine through a funnel, that will change the character of the wine. Beyond that, each winery has its own method of bottling, such as "sparging," in which bottles are filled with an inert gas before filling to ensure the right conditions.
Bucher's process involves a patent-pending technology called Total Anaerobic Sample Transfer Environment - TASTE - that aims to replicate what the winery does on a miniature scale. Transfers are conducted in a sealed, zero-oxygen chamber, similar to a semiconductor "clean room," and the goal is to come up with something that duplicates the tasting room experience.
"For us it was never about taking wine from a barrel and just putting it into a smaller vessel. That would not capture the real product that wineries are selling," Bucher says.
While it's hard to say for certain this hasn't been done, sample-size wine bottles appear to be new, says Robert Smiley, director of wine industry programs in the Graduate School of Management at the University of California, Davis. It's too early to say whether the kits will be successful, but they sound like a good idea, he says. "I'm all for innovation."
For Bucher, the power of try-and-buy wine grew out of his experiences at his own winery. Going over the books, he realized, "Wow, my tasting rooms are gold. I asked myself how could I scale my tasting rooms intergalactically."
Another player in the small-is-big trend is San Francisco-based Crushpad, the do-it-yourself winery where individuals can select fruit and supervise the making of small batches of wine to get the vintner experience without the farming headaches (and sizable capital investment).
Crushpad's "Tiny Bottles," also 50 millilitre, use an oxygen-free transfer system and are being used in conjunction with Brixr, a web-based tasting service.
At Domaine Carneros, the kits will be available in the Napa Valley tasting room - price about $25 - and also will be offered to wine club members as a convenient, low-cost way to try wines. Domaine Carneros is primarily known for its sparkling wines, so the six-bottle kits are being used to showcase its lesser-known still wines.
"We think it's a wonderful way for people to reconnect with the winery," says Crane.
-
TastingRoom: http://tastingroom.com/
Domaine Carneros: http://www.domainecarneros.com
Crushpad: http://www.crushpadwine.com/
Brixr: http://www.brixr.com

credit:technology.canoe.ca

Three ways to track your lost smartphone

You’ve lost your most prized possession: your mobile device. Don’t write it off just yet. We explain what to do when your cellphone goes missing.

1. Track it down digitally
Install iHound on your iPhone so you can keep tabs on it if it’s lost. When activated, the application uses the GPS and Wi-Fi built into the device to zero in on its location and sound an alarm. If you’re a BlackBerry or Windows Mobile device user, try GadgetTrak: It can locate your phone with GPS or data collected from cell towers. And if you’re nervous about a sticky-fingered filcher accessing your files, you can also use it to wipe data off your smart phone remotely.

2. Stick an ID tag on it
Don’t doubt the morality of your fellow citizens: An ID tag with alternative contact information could be your best hope for recovery – especially once the battery dies. If you’d rather not advertise your personal details, buy a TrackitBack tag ($20 each). The sticker displays an ID code that the finder can report through a toll-free number or website. Jason Wagner, founder of the Winnipeg-based company, says the recovery rate for lost phones outfitted with TrackitBack IDs is 85 per cent.
One TrackitBack client lost his BlackBerry at the Sydney international airport, Mr. Wagner says. On his journey back to Halifax, he called the airport at each stop to see if it had been recovered. Meanwhile, someone had found the phone and reported it to TrackitBack’s office, which had couriered it to his home in Halifax. The man and his phone were reunited in just a day and a half.

3. Report it to your service provider
Most service providers, including Bell Mobility and Rogers Wireless, recommend you call them if you lose your phone so they can block further use. You may not get your phone back (smart thieves will simply unlock the device before selling it), but this will at least prevent them from running up charges on your account.

*And don’t do this

Get out of a taxi without making sure you have your phone. It’s one of the top spots missing mobiles are found.
By the numbers
40: Percentage of U.S. and British mobile users surveyed who say they'd rather lose their wallets than their mobile devices
Source: Research firm Coleman Parkes

Nokia Symbian to get Free GPS Navigation Maps from SatGuide

Nokia Symbian to get Free GPS Navigation Maps from SatGuide

Now it is the time for Nokia users to reach their desired destination across India through GPS Navigation Software and Maps. Today SatNav Technologies, a pioneer in GPS navigation in India since 2005 has offered a free version of GPS Navigation software and Maps for Symbian OS phones by Nokia.

SatGuide Navigation maps are used highly by the branded companies such as HTC, HP, imate, ASUS, and ACER. By this launch it has become a delight for large base of Nokia users who will now be able to acces exclusive localized Indian maps and they have an option to choose from the application most suited to them.
SatGuide is an onboard solution, which allows users to avoid incurring heavy GPS subscription prices and suffer from poor GPRS connectivity which is still maturing in the country. SatGuide also offers partner’s maps for US, Canada & Europe which allow users to navigate across the globe using one single mobile device.
Plan Details:
  • Nokia users can use it free for 10 times after that if they want to continue the free service or to upgrade it, an initial one-time payment of Rs 2138 has to be made.
  • Once it is paid customers can use it lifelong without recurring charges or needing reinstallation.
  • The FREE navigation software with maps of 412+ cities of India can be downloaded from www.satguide.in
  • An incredible CASH BACK offers are provided for users when they download free version from SatNav site.
  • Rs 1000 will be paid for customers (50% discount on the regular price), if they download the software within 30 days. But this offer is time bounded.
The SatGuide Mobile Navigation Software can be installed on most Symbian OS phones by Nokia and Samsung like N95, E66, 6110, N82, 6210, E57, 6220, N78, N96, N73 and Samsung i560, among others
This software will provide an access to detailed maps for 412+ Indian cities and over 16 lakh point of interests (POI’s). Since Nokia promotes its own maps and their dealers/distributors have not been as receptive to SatGuide as compared to the response of Windows phone distributors, Nokia users were being deprived of the high quality extensive maps from SatGuide and their excellent localized after sales service and support for the Indian market.

 credit: cellbharat.com

An App That Helps You Find Your Way Is a Great Find

An App That Helps You Find Your Way Is a Great Find 


You many have noticed that GPS navigation units are deeply discounted this holiday season. The manufacturers and the stores know what customers are thinking: “Why do I need one if I can get the same technology, for a lot less money, on smartphones?”




Google's software can turn a smartphone running its Android 1.6, or later version, into a GPS unit that lets users see a wide area or a single street.

But now even the $10 monthly fee for those mobile phone apps doesn’t look like a great buy. Google began giving away navigation software that turns any smartphone running its Android 1.6 (or later) operating system into a GPS unit. That means that for now it works only on Verizon’s Droid, T-Mobile’s MyTouch 3G and G1.
But is the Google Maps Navigation app as good as Garmin or a TomTom device, and is it really cheaper? The Google app is a data hog, so you’ll need an unlimited data plan if you want to actually use the app. It’s also a battery hog, so you’ll need to pay extra for a car charger, not to mention a bracket for holding the phone.
As far as the quality of Google’s directions, during the week I tested it on the highways and back roads of Connecticut, I had only minor problems. Other users, who posted Android reviews through their smartphones, had bigger complaints — like the driver who was told by Google to turn into traffic on a one-way road.

If you spend a little time perusing the user comments of nearly any mobile navigation application, you’ll find similar complaints. That’s why it’s always smart to make good use of trial offers before committing. Since Google uses the same data for both its mobile navigation apps and its online maps service, you can basically test some online navigation searches for your home area to get a sense of how well the mobile app would do for you.
Since this is a free app, I was expecting less than I’ve seen on the paid navigation apps like AT&T Navigator, or VZ Navigator on Verizon.
But that wasn’t the case. The interface was easy enough to use, with the buttons in all the logical places. Equally easy, and pleasantly surprising, were the app’s extra features. After typing in my destination, for instance, I typed “coffee” and then “hotel” into the search box. It stuck icons onto my map for a Comfort Inn and several coffee shops — both chains and independent — along my route and nearby. If I tapped on the icon for one of them, it offered to navigate me to that spot, and it presented the phone number so that, in one tap, I could call.
I loved how, when I approached my destination, the app offered me street-level photography to help me find landmarks. With a flick of the screen, the image rotated 360 degrees.
Directions, again, weren’t perfect. On one leg of my trip, I left the highway one exit early to see how the app would reroute me. Rather than put me right back onto the entrance ramp no more than 50 yards from the exit, it steered me to a side street and a series of back roads that added probably 10 minutes to my trip.
Still, it got me there.

Google recently added a “Report a Problem” button in the app, and the company says it tries to fix those problems within a month. Users might be tempted just to scrap the software after a nightmare trip, but forgiving souls will most likely help the company improve it.
Google’s competitors in the navigation category point out that the service lacks some important features. TelMap, which builds the technology behind the MapQuest Navigator app, will offer directions even when you’ve lost your cell connection. MapQuest navigator works on a handful of smartphones, including the iPhone, the BlackBerry Curve on AT&T and the HTC Touch Diamond on Sprint.

The same is true for the Ovi Maps by Nokia application, which, incidentally, you’ll get with a free lifetime subscription if you buy the new Nokia 5800 Navigation Edition ($300 on NokiaUSA.com). Google downloads maps for your prospective route, so navigation can continue when you lose a connection. But if you become lost, it can’t find an alternate route until the connection resumes.

It’s an important consideration if you live in an area with spotty reception.
The VZ Navigator app and AT&T Navigator provide directions with a more pleasant voice than Google, which directed me in a tinny, robotic voice. Maybe Google was going for a retro effect, but in a market where apps typically feature realistic voices, this was a puzzler.
Another, more pleasant, puzzler was the complete lack of Google ads in the service. (The company has to pay for it somehow, right?) Carolyn Penner, a Google spokeswoman, would not say when the company would start running ads. Nor would she say when the turn-by-turn navigation feature would reach iPhones, BlackBerrys and other smartphones.
Users of iPhones, of course, never lack for navigation options, but many of them are either cheap and poorly rated or expensive and well reviewed. One good alternative is the Magellan RoadMate, from the company that specializes in hand-held GPS devices. It costs $80, but for that price you get perpetual software updates and a very refined service. The average user review at the Apple App store — four stars out of five — is significantly higher than those for competitors. After a few problem-free runs with the app myself, I’d offer only a slightly less generous rating.
Compared with a $10 monthly subscription, the RoadMate is a stellar deal. That is, at least until Google’s navigation app makes its way onto the iPhone.
Quick Calls
For people constantly misplacing their Bluetooth headset, the MoGo Talk for iPhone is a headset that attaches to an iPhone shell. The headset features a hinged boom and noise-canceling technology, and the shell doubles as a protective case ($129 MogoTalk.com). ... If you are comfortable handing your BlackBerry to your baby, Baby Go!, a free app from Zeebu Mobile, is made for children 2 years old and younger. As letter blocks move around the screen, a speaker pronounces the name of the letter. The app shuts off the child’s access to e-mail or the phone’s dial pad (zeebu.com).... Super Dreidel, a new $1 iPhone app, simulates the traditional Hanukkah game, and includes a full set of rules and a score tracker to cut down on arguments. In case you’re wondering, the game does not involve spinning your phone — swipe the screen and an animated dreidel twirls.

By BOB TEDESCHI , Nytimes.com
 

Copyright 2008-2012 GPS News and GIS News | Back To :Gps News | Bankruptcy Lawyer Help | Fixed Gear Bike Store | Shoes Shop | PreOrder Thai Suit Shop for Men